Side Effects:-
Applies to amantadine: oral capsule, oral capsule extended release, oral capsule liquid filled, oral syrup, oral tablet, oral tablet extended release
Along with its needed effects, amantadine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking amantadine:
More Common
Bladder pain
bloody or cloudy urine
blurred vision
confusion
difficult, burning, or painful urination
dizziness or lightheadedness
fainting
falls
frequent urge to urinate
lower back or side pain
seeing, hearing, or feeling things that are not there
swelling of the hands, feet, or lower legs
Less Common
Inability to move the eyes
increased blinking or spasms of the eyelid
muscle spasm
sticking out of the tongue
troubled breathing, speaking, or swallowing
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual facial expressions
Rare
Chills
decreased vision or any change in vision
difficulty in coordination
fever
increased blood pressure
increase in body movements
irritation and swelling of the eye
loss of memory
mental depression
seizures
severe mood or mental changes
skin rash
slurred speech
sore throat
thoughts of suicide or attempts at suicide
Some side effects of amantadine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More Common
Agitation
anxiety
difficulty concentrating
headache
irritability
loss of appetite
nausea
nervousness
nightmares
purplish red, net-like, or blotchy spots on the skin
trouble with sleeping
Less Common
Constipation
decrease in sexual desire
diarrhea
drowsiness
dryness of the mouth, nose, and throat
false sense of well-being
unusual tiredness or weakness
vomiting
General
The more commonly reported adverse reactions have included nausea, dizziness/lightheadedness, and insomnia.[Ref]
Nervous system
Common (1% to 10%): Dizziness/lightheadedness, ataxia, headache, somnolence, dystonia
Overview
Dystonia is a movement disorder in which your muscles contract involuntarily, causing repetitive or twisting movements.
The condition can affect one part of your body (focal dystonia), two or more adjacent parts (segmental dystonia) or all parts of your body (general dystonia). The muscle spasms can range from mild to severe. They may be painful, and they can interfere with your performance of day-to-day tasks.
There's no cure for dystonia. But medications can improve symptoms. Surgery is sometimes used to disable or regulate nerves or certain brain regions in people with severe dystonia.
Symptoms
Dystonia affects different people in varying ways. Muscle contractions might:
Begin in a single area, such as your leg, neck or arm. Focal dystonia that begins after age 21 usually starts in the neck, arm or face and tends to remain focal or segmental.
Occur during a specific action, such as handwriting.
Worsen with stress, fatigue or anxiety.
Become more noticeable over time.
Areas of the body that can be affected include:
Neck (cervical dystonia). Contractions cause your head to twist and turn to one side, or pull forward or backward, sometimes causing pain.
Eyelids. Rapid blinking or involuntary spasms cause your eyes to close (blepharospasms) and make it difficult for you to see. Spasms usually aren't painful but might increase when you're in bright light, under stress or interacting with people. Your eyes might feel dry.
Jaw or tongue (oromandibular dystonia). You might experience slurred speech, drooling, and difficulty chewing or swallowing. Oromandibular dystonia can be painful and often occurs in combination with cervical dystonia or blepharospasms.
Voice box and vocal cords (spasmodic dystonia). You might have a tight or whispering voice.
Hand and forearm. Some types of dystonia occur only while you do a repetitive activity, such as writing (writer's dystonia) or playing a specific musical instrument (musician's dystonia).