I must admit when the vaccines were intially rolled out I was a little sceptical based on the speed of the rollouts and whether they had undergone the sort of rigorous testing they would normally undergo before given the go ahead. Being down the pecking order in terms of priority I was satisfied enough guinea pigs had gone before! Also I understand the AZ vaccine is similar to vaccines received in the past for childhood illnesses and travel.
My understanding is that UK boosters are Moderna or Pfizer/BioNTech vaccines not AZ which are based on different technologies and cause the immune system to react differently in the invent of infection. Has the mix n match approach been sufficiently tested for efficacy, safety and more importantly that this approach itself isn't going to generate some frankenstein mutation?